Laboratories of CNS members

Laboratory of Pain Research

Institute of Physiology, Czech Academy of Sciences

We study pain mechanisms and explore new possibilities of pain treatment using electrophysiological, optogenetic, immunohistochemical and behavioral methods.

PI: Jiri Palecek

Laboratory of Biological Rhythms

Institute of Physiology, Czech Academy of Sciences

We are investigating the molecular mechanism for entraining the circadian system in mammals, including humans, and the consequences of its failure on our health, from the fetal stage to old age.

PI: Alena Sumova

Laboratory for Experimental Neurophysiology

Faculty of Medicine in Pilsen, Charles University

Using large scale neural unit recordings we study information coding in the brain, mechanisms of memory, spatial navigation and pathophysiology of Alzheimer Disease, Sepsis and Schizophrenia.

PI: Karel Jezek

Laboratory of Cholinergic Signaling

Institute of Physiology of the Czech Academy of Sciences

We investigate the expression and function of acetylcholine receptors in individual neuronal populations. We aim to explore the complexity of acetylcholine receptors to pave the way to new therapeutic approaches.

PI: Helena Janickova

Laboratory of Cellular Neurophysiology

Institute of Physiology of the Czech Academy of Sciences

We study ionotropic glutamate receptors and TRP channels, key mediators of excitatory signaling, brain function, pain sensing, inflammation, and GRIN-related neuropsychiatric disorders.

PI: Ladislav Vyklicky

Laboratory of Molecular Neurobiology

Institute of Physiology of the Czech Academy of Sciences

We investigate microtubule-associated proteins and microtubule regulation in brain connectivity formation and in neurodevelopmental disorders using molecular, cellular, and animal models.

PI: Martin Balastik

Laboratory of Neuroregeneration

Institute of Experimental Medicine of the Czech Academy of Sciences

We are studying the potential of regeneration and repair of nerve tissue in cases of injury and neurodegenerative diseases, including in vitro and in vivo models.

PI: Pavla Jendelova

Laboratory of Sleep, chronobiology and behavior in animal models

National Institute of Mental Health

Our laboratory focuses on preclinical research in animal models of psychiatric disorders, such as schizophrenia, autism and Alzheimer's disease, and the development of new therapeutic approaches.

PI: Tomas Petrasek

Laboratory of Neurochemistry

Institute of Experimental Medicine of the Czech Academy of Sciences

We study the regulation and function of NMDA receptors using electrophysiology, microscopy and behavioral methods. We aim to understand their complexity and develop therapies for related disorders.

PI: Martin Horak

Spatial Cognition Laboratory

Department of Neurology, Second Faculty of Medicine, Charles University, Motol and Homolka University Hospital

The laboratory focuses on assessing spatial orientation as a cognitive marker of the early stages of neurodegenerative diseases using tests conducted in real-world and virtual environments.

PI: Jan Laczó

Laboratory of Computational Neuroscience

Institute of Physiology of the Czech Academy of Sciences

We use methods from information theory, stochastic processes, differential equations, and statistics to describe processes in nervous systems at the level of individual cells and cell populations.

PI: Lubomir Kostal